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Singleron Biotechnologies

Founded in 2018, Singleron develops and commercializes single cell multi-omics products that can be used in both research and clinical settings. Its current product portfolio includes instruments, microfluidic devices, reagents, software analysis and database solutions that facilitate high-throughput single cell analysis. The company currently has offices, laboratories, and manufacturing facilities in Germany, Singapore, China, and the US. Its products are used in over 2,000 laboratories in hospitals, research institutes, and pharmaceutical companies.

Singleron’s proprietary SCOPE technology comprises the entire process from fresh tissue preservation and dissociation, automated single cell partition and barcoding, to the subsequent library preparation and bioinformatic analysis. With our innovative single cell transcriptome and multi-omics solutions, we enable clinical researchers to translate deep insights of diseases into guidance for medical practice.

To better elucidate the connection between genotype and gene expression patterns in same cells, Singleron has developed a multi-omics solution, FocuSCOPEÒ, to detect both target sequences of interest and transcriptome simultaneously at single cell resolution. Our technology is based on unique barcoding beads conjugated with oligos to efficiently capture targeted gene transcripts along with the whole transcriptome, improving the detection rate of target sequences of interest, genetic variants, mutations, or gene fusions.

Singleron’s products and applications are also offered as single cell sequencing service. With our European service lab conveniently located in Cologne, Germany, we provide a one-stop-shop for single cell sequencing covering all steps from project design and sample processing to bioinformatic analysis and interpretation of results for publication-ready data. Singleron focuses strongly on processing clinical sample types, with an overall high success rate of 94% on over 8,000 samples. Our experience comes with having processed more than 660 different tissue types, including challenging samples such as needle biopsies.